1'-hydroxybufuralol

 
National Institutes of Health

Topic mentions per year

Topic mentions per year

1987-2013
012319872013

Papers overview

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2013
2013
The goal of this study was to assess in human liver microsomes the inhibitory capacity of commonly used antipsychotics on the… (More)
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2011
2011
A three-phase hollow-fiber liquid-phase microextraction (HF-LPME) method for the stereoselective determination of bufuralol… (More)
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2006
2006
A reverse-phase, high-performance liquid chromatography method is described for the quantification of 1'-hydroxybufuralol formed… (More)
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2004
2004
Human liver microsomes (HLMs) are frequently utilized in drug discovery to predict the human clearance of a compound. The extent… (More)
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2003
2003
A method has been developed for the high-throughput inhibition screening of the major human cytochrome P450 (CYP) enzymes (CYP1A2… (More)
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2002
2002
In rats, six cytochrome P450 (P450) 2D isoforms have been genetically identified. Nonetheless, there is little evidence of… (More)
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2001
2001
Debrisoquine metabolism among Tanzanians has been found to be slower than expected from the CYP2D6 genotype. In order to evaluate… (More)
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1999
1999
The cynomolgus monkey is a species used in drug-safety evaluation and biotransformation studies by the pharmaceutical industry… (More)
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1994
1994
Bufuralol 1'-hydroxylation is a prototypical reaction catalyzed by cytochrome P450 (P450) 2D6, an enzyme known to show… (More)
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Highly Cited
1987
Highly Cited
1987
Bufuralol, debrisoquine, and dextromethorphan are three prototype substrates of the common genetic deficiency of oxidative drug… (More)
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