1'-acetoxysafrole

We have used an oriP-tk shuttle vector to determine the types of mutations induced in human cells by ethyl methanesulfonate (EMS… Expand

Further information on the structure-activity relationships among the synthetic and naturally occurring alkenylbenzene… Expand

The identities of the adducts formed on reaction of the model electrophilic and carcinogenic esters 1'-acetoxysafrole or 1… Expand

The binding of a series of alkenylbenzenes to liver DNA of adult female CD-1 mice, isolated 24 h after i.p. administration of non… Expand

Administration of 1'-[2'-3'-3H]hydroxysafrole to adult female mice resulted in the formation of DNA-, ribosomal RNA-, and protein… Expand

Safrole, estragole, anethole, and eugenol and some of their known or possible metabolites were tested for mutagenic activity for… Expand

Approximately 20% of a dose of estragole, a naturally occurring flavoring agent, was excreted in the urine of outbred male CD -1… Expand

Administration of [2',3'-3H]-1'-hydroxysafrole to rats or mice resulted in the formation of hepatic DNA-, ribosomal RNA-, and… Expand

We described previously a simple test on petri plates for detecting chemical carcinogens as mutagens, using an especially… Expand

A conjugated form of 1′-hydroxysafrole was identified as a urinary metabolite of safrole; the conjugate was cleaved by commercial… Expand