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1'-(hydroxymethyl)eugenol

Known as: 1'-hydroxymethyleugenol 
 
National Institutes of Health

Papers overview

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2017
2017
Previously the food carcinogen methyleugenol was found to be cytotoxic and genotoxic in multiple cell lines and in primary… Expand
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2015
2015
The present study aims at predicting the level of formation of the ultimate carcinogenic metabolite of methyleugenol, 1… Expand
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2014
2014
Methyleugenol--a natural constituent of herbs and spices--is hepatocarcinogenic in rodent models. It can form DNA adducts after… Expand
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2013
2013
Methyleugenol (ME) occurs naturally in a variety of spices, herbs, including basil, and their essential oils. ME induces… Expand
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2012
2012
This study defines a physiologically based kinetic (PBK) model for methyleugenol (ME) in human based on in vitro and in silico… Expand
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2012
2012
Methyleugenol is a substituted alkenylbenzene classified by the European Union's Scientific Committee on Food as a genotoxic… Expand
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2011
2011
The present study defines a physiologically based biokinetic (PBBK) model for the alkenylbenzene methyleugenol in rat based on in… Expand
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2006
2006
In vitro studies were performed to elucidate the human cytochrome P450 enzymes involved in the bioactivation of methyleugenol to… Expand
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1997
1997
Cytochrome P450 mediated metabolism of methyleugenol to the proximate carcinogen 1'-hydroxymethyleugenol has been investigated in… Expand
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1996
1996
Methyleugenol is an allylbenzene food flavoring which has been shown to form DNA and protein adducts, and to cause hepatotoxicity… Expand
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