[hydroxymethylglutaryl-CoA reductase (NADPH)] kinase activity

Known as: 3-hydroxy-3-methylglutaryl coenzyme A reductase kinase activity, hydroxymethylglutaryl-CoA reductase (NADPH2) kinase activity, AMPK 
Catalysis of the reaction: [3-hydroxy-3-methylglutaryl-CoA reductase (NADPH)] + ATP = [3-hydroxy-3-methylglutaryl-CoA reductase (NADPH)] phosphate… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1969-2017
05101519692017

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2004
Highly Cited
2004
OBJECTIVES This study aimed to investigate the impact of hydroxymethylglutaryl coenzyme A reductase inhibitor (statin) therapy in… (More)
  • table 1
  • table 3
  • table 4
Is this relevant?
Highly Cited
2003
Highly Cited
2003
Several prospective clinical studies have indicated that hydroxymethylglutaryl-coenzyme A reductase inhibitors, statins, prevent… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 6
Is this relevant?
Highly Cited
2003
Highly Cited
2003
Recent epidemiological studies revealed inhibitors of the hydroxymethylglutaryl-coenzyme A reductase, so-called statins, to be… (More)
Is this relevant?
Highly Cited
2002
Highly Cited
2002
BACKGROUND The early response of C-reactive protein to initiation of a hydroxymethylglutaryl coenzyme A reductase inhibitor… (More)
  • table 1
  • figure 1
  • table 2
  • figure 2
  • figure 3
Is this relevant?
Highly Cited
2001
Highly Cited
2001
BACKGROUND Long-term therapy with hydroxymethylglutaryl coenzyme A reductase inhibitors (statins) has been shown to reduce levels… (More)
  • table 1
  • table 2
Is this relevant?
Highly Cited
2001
Highly Cited
2001
BACKGROUND Hydroxymethylglutaryl coenzyme A reductase inhibitors (statins) attenuate angiotensin II-induced cellular signaling… (More)
  • table 1
  • table 2
  • figure 1
  • figure 2
Is this relevant?
Highly Cited
2001
Highly Cited
2001
BACKGROUND The short-term effects of hydroxymethylglutaryl coenzyme A reductase inhibitors (statins) on endothelial function at… (More)
  • figure 1
  • figure 2
Is this relevant?
Highly Cited
2001
Highly Cited
2001
BACKGROUND Elevated oxidative stress and superoxide anion formation in vascular cells could promote conversion of LDL to… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 5
  • figure 6
Is this relevant?
Highly Cited
2000
Highly Cited
2000
BACKGROUND In patients with atherosclerosis, hepatic hydroxymethylglutaryl coenzyme A reductase (CSE) inhibitors may reduce the… (More)
Is this relevant?
Highly Cited
1984
Highly Cited
1984
Support for the role of a cytosolic oxysterol-binding protein in the regulation of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA… (More)
Is this relevant?