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(R)-dehydropantoate dehydrogenase activity

Known as: (R)-4-dehydropantoate:NAD+ 4-oxidoreductase activity, D-2-hydroxy-3,3-dimethyl-3-formylpropionate:diphosphopyridine nucleotide (DPN+) oxidoreductase activity, D-aldopantoate dehydrogenase activity 
Catalysis of the reaction: (R)-4-dehydropantoate + H(2)O + NAD(+) = (R)-3,3-dimethylmalate + 2 H(+) + NADH. [EC:1.2.1.33, RHEA:19352]
National Institutes of Health

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1984
1984
The reaction of 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide with an essential carboxy group of human placental estradiol 17 beta-dehydrogenase.
Estradiol 17 beta-dehydrogenase from human placenta was inactivated by 1-ethyl-3-(3-dimethylaminopropyl) carbodiimide (EDC), a… 
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