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(124)I-cMAb U36

Known as: 124I-cMAb U36 
 
National Institutes of Health

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Monoclonal AntibodiescMAb U36

Papers overview

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Highly Cited
2009
Highly Cited
2009
Radiation dosimetry of 89Zr-labeled chimeric monoclonal antibody U36 as used for immuno-PET in head and neck cancer patients.
UNLABELLED Immuno-PET is an appealing concept in the detection of tumors and planning of antibody-based therapy. For this purpose… Expand
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2006
2006
Immuno-PET of undifferentiated thyroid carcinoma with radioiodine-labelled antibody cMAb U36: application to antibody tumour uptake studies
PurposeWe tested the suitability of the chimeric monoclonal anti-human CD44 splice version 6 antibody (cMAb U36) for targeting… Expand
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2005
2005
In vitro evaluation of the astatinated chimeric monoclonal antibody U36, a potential candidate for treatment of head and neck squamous cell carcinoma
PurposeThe purpose of this study was to analyse the properties of the astatinated chimeric MAb (cMAb) U36 as a conjugate to… Expand
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2004
2004
High-quality 124I-labelled monoclonal antibodies for use as PET scouting agents prior to 131I-radioimmunotherapy
PurposeMonoclonal antibodies (MAbs) labelled with 124I are an attractive option for quantitative imaging with positron emission… Expand
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2003
2003
Biodistribution of the chimeric monoclonal antibody U36 radioiodinated with a closo-dodecaborate-containing linker. Comparison with other radioiodination methods.
We have evaluated the applicability of the [(4-isothiocyanatobenzylammonio)undecahydro-closo-dodecaborate (1-)] (DABI) linker… Expand
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2002
2002
Reinfusion of unprocessed, granulocyte colony-stimulating factor-stimulated whole blood allows dose escalation of 186Relabeled chimeric monoclonal antibody U36 radioimmunotherapy in a phase I dose…
PURPOSE In an earlier Phase I radioimmunotherapy (RIT) study with rhenium-186-labeled chimeric monoclonal antibody (cMAb) U36 in… Expand
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2001
2001
Radioimmunotherapy in patients with head and neck squamous cell carcinoma: initial experience.
BACKGROUND Despite improvements in locoregional treatment of stages III/IV squamous cell carcinoma of the head and neck (HNSCC… Expand
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2000
2000
Phase I therapy study of 186Re-labeled chimeric monoclonal antibody U36 in patients with squamous cell carcinoma of the head and neck.
UNLABELLED A phase I therapy study was conducted to determine the safety, maximum tolerated dose (MTD), pharmacokinetics… Expand
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2000
2000
Targeting of a hydrophilic photosensitizer by use of internalizing monoclonal antibodies: A new possibility for use in photodynamic therapy.
Coupling of photosensitizers to tumor-selective monoclonal antibodies (MAbs) is an attractive option for improving the… Expand
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1997
1997
Rapid elimination of mouse/human chimeric monoclonal antibodies in nude mice
Abstract At our laboratory we are currently evaluating the suitability of mouse/human chimeric monoclonal antibodies (cmAb) for… Expand
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