(11C)N-desmethyl-loperamide

Known as: (11C)dLop, Carbon C 11 N-desmethyl-Loperamide 
A radiopharmaceutical containing N-desmethyl loperamide (dLop) labeled with carbon 11 (11C), used to measure the activity of efflux transporter P… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1971-2017
010203019712017

Papers overview

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Highly Cited
2009
Highly Cited
2009
INTRODUCTION We investigated placental transfer and neurobehavioural effects in neonates exposed to citalopram, escitalopram… (More)
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2008
2008
UNLABELLED Loperamide, an opiate receptor agonist, does not cross the blood-brain barrier because it is a substrate for the… (More)
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2008
2008
We sought to develop (11)C-labeled ligands for sensitive imaging of brain peripheral benzodiazepine receptors (PBR) in vivo. Two… (More)
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Highly Cited
2008
Highly Cited
2008
Ambient ionization methods for MS enable direct, high-throughput measurements of samples in the open air. Here, we report on one… (More)
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Highly Cited
2004
Highly Cited
2004
The antiestrogen tamoxifen is extensively metabolized in patients to form a series of compounds with altered affinity for… (More)
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Highly Cited
2003
Highly Cited
2003
Background: Tamoxifen, a selective estrogen receptor modulator (SERM), is converted to 4-hydroxy-tamoxifen and other active… (More)
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2003
2003
Our aim was to investigate possible interaction between gemfibrozil and rosiglitazone, a thiazolidinedione antidiabetic drug. In… (More)
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Highly Cited
2000
Highly Cited
2000
The soy isoflavones, daidzein and genistein, and the lignans, matairesinol and secoisolariciresinol, are phytoestrogens… (More)
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Highly Cited
2000
Highly Cited
2000
An in vitro model is proposed to account for the clinically observed inhibition of cytochrome P450 (CYP) 3A that results from… (More)
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1996
1996
The interactions in vitro of LY307640 with the cytochromes P450 (P450s) were studied using human liver microsomes, specific… (More)
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