zen and the art of phenotypic maintenance: Canalization of embryonic dorsal-ventral patterning in Drosophila

Abstract

We recently uncovered a novel genetic mechanism that generates the phenotypic uniformity, or canalization, of BMP signaling and cell fate specification during patterning of the dorsal-ventral (D/V) axis in D. melanogaster embryos. We went on to show that other wild-type Drosophila species lack this canalizing genetic circuitry and, consequently, have non… (More)
DOI: 10.4161/19336934.2014.983385

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