xi-Aminocaproic acid: an inhibitor of plasminogen activation.

@article{Alkjaersig1959xiAminocaproicAA,
  title={xi-Aminocaproic acid: an inhibitor of plasminogen activation.},
  author={Norma Alkjaersig and Anthony P. Fletcher and Sol Sherry},
  journal={The Journal of biological chemistry},
  year={1959},
  volume={234 4},
  pages={
          832-7
        }
}
Human and animal sera contain a globulin, plasminogen, which in the presence of activators is rapidly converted to plasmin, a proteolytic enzyme active at neutral hydrogen ion concentrations. Activators specific for plasminogen include streptokinase and staphylokinase of bacterial origin, urokinase and plasma activator found in body fluids, and fibrinokinase derived from tissues. Trypsin, an activator of other enzyme systems, will activate plasminogen, and plasminogen may undergo spontaneous… CONTINUE READING

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SHOWING 1-10 OF 40 CITATIONS

DESTRUCTION OF EPIDERMAL CELLS IN VITRO BY AUTOLOGOUS SERUM FROM NORMAL ANIMALS

  • The Journal of experimental medicine
  • 1962
VIEW 5 EXCERPTS
CITES BACKGROUND
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The mechanism of clot dissolution by plasmin.

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  • 1959
VIEW 4 EXCERPTS
CITES METHODS & BACKGROUND

THE ENHANCEMENT OF CHLOROFORM-INDUCED PLASMA PROTEOLYTIC ACTIVITY BY EPSILON AMINOCAPROIC ACID

  • The Journal of experimental medicine
  • 1962
VIEW 4 EXCERPTS
CITES BACKGROUND
HIGHLY INFLUENCED

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