wTO: an R package for computing weighted topological overlap and a consensus network with integrated visualization tool

  title={wTO: an R package for computing weighted topological overlap and a consensus network with integrated visualization tool},
  author={Deisy Morselli Gysi and Andr{\'e} Voigt and Tiago de Miranda Fragoso and Eivind Almaas and Katja Nowick},
  journal={BMC Bioinformatics},
BackgroundNetwork analyses, such as of gene co-expression networks, metabolic networks and ecological networks have become a central approach for the systems-level study of biological data. [] Key Method The package includes the calculation of p-values (raw and adjusted) for each pairwise gene score. Our package also allows the calculation of networks from time series (without replicates). Since networks from independent datasets (biological repeats or related studies) are not the same due to technical and…

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