von Willebrand factor. A protein which binds at the cell surface interface between platelets.

Abstract

von Willebrand factor (VWF) functions in platelet aggregation, a form of cellular interaction. In vitro analysis of platelet aggregation, as measured by the platelet aggregometer, requires addition of a promoter such as the glycopeptide antibiotic ristocetin. Native multimeric VWF (Mr = 1-20 X 10(6)) can be reduced with sulfhydryl reagents to a monomeric… (More)

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@article{Senogles1983vonWF, title={von Willebrand factor. A protein which binds at the cell surface interface between platelets.}, author={Susan E. Senogles and Gary L. Nelsestuen}, journal={The Journal of biological chemistry}, year={1983}, volume={258 20}, pages={12327-33} }