v-Src Causes Chromosome Bridges in a Caffeine-Sensitive Manner by Generating DNA Damage

Abstract

An increase in Src activity is commonly observed in epithelial cancers. Aberrant activation of the kinase activity is associated with malignant progression. However, the mechanisms that underlie the Src-induced malignant progression of cancer are not completely understood. We show here that v-Src, an oncogene that was first identified from a Rous sarcoma… (More)
DOI: 10.3390/ijms17060871

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