use of Exercise for Treatment of Chronic Fatigue Syndrome

  title={use of Exercise for Treatment of Chronic Fatigue Syndrome},
  author={Kevin K McCully and Sue A. Sisto and B. H. Natelson},
  journal={Sports Medicine},
SummaryChronic fatigue syndrome (CFS) is a condition that results in moderate to severe disability, the primary feature of which is fatigue of unknown origin. There is a lot of interest in classifying, characterising and treating patients with CFS. Currently, the two major theories of a medical cause of CFS are viral infection and immune dysregulation. Patients report critical reductions in levels of physical activity, and many experience ‘relapses’ of severe symptoms following even moderate… 

The effectiveness of interventions used in the treatment/management of chronic fatigue syndrome and/or myalgic encephalomyelitis in adults and children

The effectiveness of all available interventions which have been evaluated for use in the treatment or management of adults and children with CFS/ME is evaluated.

Chronic Fatigue Syndrome

Prevention of overtraining by careful monitoring seems the most effective approach in athletes, and treatment should aim at breaking the vicious cycle of effort avoidance, deterioration in physical condition and an increase in fatigue through a combination of encouragement and a progressive exercise programme.

The role of deconditioning and therapeutic exercise in chronic fatigue syndrome (CFS)

A non-systematic review of published papers concerning deconditioning and therapeutic exercise in patients with chronic fatigue syndrome concluded that graded exercise has an important role to play in the treatment of patients with CFS.

Myalgic encephalomyeltitis/chronic fatigue syndrome: rehabilitation through activity management, stress management and exercise therapy

The present manuscript uses ME/CFS to acknowledge the lack of an appropriate name for this severely underestimated illness and uses the current understanding of the illness to provide guidelines for applying rehabilitation to those with ME/ CFS.

Exercise capacity in chronic fatigue syndrome.

Reaching the age-predicted target heart rate seemed to be a limiting factor of the patients with CFS in achieving maximal effort, which could be due to autonomic disturbances.

Chronic fatigue syndrome: lack of association between pain-related fear of movement and exercise capacity and disability.

Results indicate a lack of correlation between kinesiophobia and exercise capacity, activity limitations, or participation restrictions, at least in patients with CFS who are experiencing widespread muscle or joint pain.

Can exercise limits prevent post-exertional malaise in chronic fatigue syndrome? An uncontrolled clinical trial

It was shown that the use of exercise limits (limiting both the intensity and duration of exercise) prevents important health status changes following a walking exercise in people with chronic fatigue syndrome, but was unable to prevent short-term symptom increases.

Chronic fatigue syndrome.

Hypothalamic-Pituitary-Adrenal (HPA) Axis and Chronic Fatigue Syndrome in Older Adults: The Rehabilitation Perspectives

With proper coaching and regular facilitation regarding AS, activity participation in older adults with CFS can be greatly enhanced, and Behavioral intervention, such as AS, can supplement therapeutic treatment or may lead to decline in CFS symptoms.



Muscle histopathology and physiology in chronic fatigue syndrome.

There was no consistent correlation between symptoms and changes in fibre type prevalence, fibre size, degenerative or regenerative features, glycogen depletion, or mitochondrial abnormalities, and it is clear that CFS is not a myopathy.

The Chronic Fatigue Syndrome: A Comprehensive Approach to Its Definition and Study

We have developed a conceptual framework and a set of research guidelines for use in studies of the chronic fatigue syndrome. The guidelines cover the clinical and laboratory evaluation of persons

Prevalence of fatigue and chronic fatigue syndrome in a primary care practice.

While chronic, debilitating fatigue is common in medical outpatients, CFS is relatively uncommon and depends substantially on the case definition used.

Unproven diet therapies in the treatment of the chronic fatigue syndrome.

Until the results of studies demonstrating the benefits of particular diet therapies in the management of C FS are available, patients with CFS are advised to eat a varied diet selected from among and within the basic food groups to ensure an adequate nutrient intake and to reach and maintain a reasonable body weight.

Chronic fatigue in primary care. Prevalence, patient characteristics, and outcome.

The high prevalence, persistence, and functional consequences of fatigue mandate a search for effective therapy.

Cognitive and mood-state changes in patients with chronic fatigue syndrome.

It is concluded that while acute mononucleosis and infection with Epstein-Barr virus occasionally result in impaired cognition, such changes have not yet been objectively verified in patients with CFS.

Exercise performance and fatiguability in patients with chronic fatigue syndrome.

Raised perceived exertion scores during exercise suggest that central factors are limiting exercise capacity in patients with chronic fatigue syndrome.

Assessment of depression in patients with chronic fatigue syndrome.

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    Reviews of infectious diseases
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Assessment should focus on the symptoms and syndromes of depressive disorder, utilization of a single rating scale to assess presumed depression is discouraged, and alternate approaches to classification that allow for symptomatic overlap of a major depressive disorder and CFS are suggested.

Acylcarnitine deficiency in chronic fatigue syndrome.

It is shown that patients with CFS had a deficiency of serum acylcarnitine, which might induce an energy deficit and/or abnormality of the intramitochondrial condition in the skeletal muscle, thus resulting in general fatigue, myalgia, muscle weakness, and postexertional malaise in patients withCFS.