uPA dependent and independent mechanisms of wound healing by C-phycocyanin

@inproceedings{Madhyastha2008uPADA,
  title={uPA dependent and independent mechanisms of wound healing by C-phycocyanin},
  author={Harishkumar Madhyastha and Kodali Radha and Yuichi Nakajima and Sayuri Omura and Masugi Maruyama},
  booktitle={Journal of cellular and molecular medicine},
  year={2008}
}
Wound repair requires both recruitment and well co-ordinated actions of many cell types including inflammatory cells, endothelial cells, epithelial cells and importantly fibroblast cells. Urokinase-type plasminogen activator (uPA) system plays a vital role in wound healing phenomenon. We have previously demonstrated that C-phycocyanin (C-pc), a biliprotein from blue-green algae, transcriptionally regulates uPA through cAMP-dependent protein kinase A (PKA) pathway. To date, a role for C-pc in… CONTINUE READING
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