trans,trans-muconic acid as a biomarker of non-occupational environmental exposure to benzene.

@article{Ruppert1997transtransmuconicAA,
  title={trans,trans-muconic acid as a biomarker of non-occupational environmental exposure to benzene.},
  author={Thomas Ruppert and Gerhard Scherer and Anthony R. Tricker and Franz Adlkofer},
  journal={International archives of occupational and environmental health},
  year={1997},
  volume={69 4},
  pages={247-51}
}
Excretion of trans,trans-muconic acid (2,4-hexadienedioic acid; t,t-MA), a potential biomarker of low-level exposure to benzene, was determined in 32 smokers and 82 nonsmokers. In smokers the median background excretion of t,t-MA was 0.13 (0.06-0.39) mg/g creatinine and was significantly higher (P < 0.05) than the value of 0.065 (0.02-0.59) mg g creatinine in nonsmokers. For nonsmokers, the correlation between t,t-MA excretion and environmental exposure to benzene in ambient air, which was… CONTINUE READING

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