the electrochemistry and cytotoxicity of the natural product marcanine A and its synthetic derivatives †

The electrochemistry and cytotoxicity of marcanine A were investigated by electrochemical, computational and cellular studies. To enable a structure–toxicity-relationship of the natural product, eleven novel synthetic derivatives with different electrochemical properties were synthesized and tested. Derivative 5 revealed a GI50 in the low mM range, being… CONTINUE READING