tRNAs and proteins are imported into mitochondria of Trypanosoma brucei by two distinct mechanisms.

@article{Nabholz1999tRNAsAP,
  title={tRNAs and proteins are imported into mitochondria of Trypanosoma brucei by two distinct mechanisms.},
  author={Christoph E. Nabholz and Elke K. Horn and Andr{\'e} Schneider},
  journal={Molecular biology of the cell},
  year={1999},
  volume={10 8},
  pages={
          2547-57
        }
}
Import of tRNA into the mitochondrial matrix of Trypanosoma brucei was reconstituted in vitro. Efficient import required the hydrolysis of externally added ATP and was shown to be a carrier-mediated process depending on proteinaceous receptors on the surface of mitochondria. A partly synthetic tRNA(Tyr) as well as a physiological tRNA(Lys) were imported along the same pathway. Contrary to import of all matrix-localized proteins, tRNA import does not require a membrane potential. Furthermore… CONTINUE READING
13 Citations
47 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 13 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 47 references

Similar Papers

Loading similar papers…