tRNA punctuation model of RNA processing in human mitochondria

@article{Ojala1981tRNAPM,
  title={tRNA punctuation model of RNA processing in human mitochondria},
  author={D. Ojala and Julio Montoya and G. Attardi},
  journal={Nature},
  year={1981},
  volume={290},
  pages={470-474}
}
  • D. Ojala, Julio Montoya, G. Attardi
  • Published 1981
  • Biology, Medicine
  • Nature
  • A 3′-end proximal segment of most of the putative mRNAs encoded in the heavy strand of HeLa cell mtDNA has been partially sequenced and aligned with the DNA sequence. In all cases, the 3′-end nucleotide of the individual mRNA coding sequences has been found to be immediately contiguous to a tRNA gene or another mRNA coding sequence. These and previous results indicate that the heavy (H) strand sequences coding for the rRNA, poly (A)-containing RNA and tRNA species form a continuum extending… CONTINUE READING
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    References

    SHOWING 1-10 OF 31 REFERENCES
    DNA sequence of a T4 transfer RNA gene cluster.
    • 45
    Fine mapping of the ribosomal RNA genes of HeLa cell mitochondrial DNA.
    • 17
    Sequence and organization of the human mitochondrial genome
    • 8,149
    Ribonuclease P substrate specificity: cleavage of a bacteriophage phi80-induced RNA.
    • 44
    • PDF