tRNA dynamics between the nucleus, cytoplasm and mitochondrial surface: Location, location, location.

@article{Chatterjee2018tRNADB,
  title={tRNA dynamics between the nucleus, cytoplasm and mitochondrial surface: Location, location, location.},
  author={Kunal Chatterjee and Regina T Nostramo and Yao Wan and Anita K Hopper},
  journal={Biochimica et biophysica acta},
  year={2018},
  volume={1861 4},
  pages={
          373-386
        }
}
Although tRNAs participate in the essential function of protein translation in the cytoplasm, tRNA transcription and numerous processing steps occur in the nucleus. This subcellular separation between tRNA biogenesis and function requires that tRNAs be efficiently delivered to the cytoplasm in a step termed "primary tRNA nuclear export". Surprisingly, tRNA… CONTINUE READING