tRNA determinants for transcription antitermination of the Bacillus subtilis tyrS gene.

@article{Grundy2000tRNADF,
  title={tRNA determinants for transcription antitermination of the Bacillus subtilis tyrS gene.},
  author={Frank J. Grundy and Jennifer A. Collins and Sean M. Rollins and Tina M. Henkin},
  journal={RNA},
  year={2000},
  volume={6 8},
  pages={1131-41}
}
Transcriptional regulation of the T box family of aminoacyl-tRNA synthetase and amino acid biosynthesis genes in Gram-positive bacteria is mediated by a conserved transcription antitermination system, in which readthrough of a termination site in the leader region of the mRNA is directed by a specific interaction with the cognate uncharged tRNA. The specificity of this interaction is determined in part by pairing of the anticodon of the tRNA with a "specifier sequence" in the leader, a codon… CONTINUE READING