tRNA's modifications bring order to gene expression.

@article{Gustilo2008tRNAsMB,
  title={tRNA's modifications bring order to gene expression.},
  author={Estella M. Gustilo and Franck A. P. Vendeix and Paul F. Agris},
  journal={Current opinion in microbiology},
  year={2008},
  volume={11 2},
  pages={134-40}
}
The posttranscriptional modification of RNA is a significant investment in genes, enzymes, substrates, and energy. Advances in molecular genetics and structural biology indicate strongly that modifications of tRNA's anticodon domain control gene expression. Modifications at the anticodon's wobble position are required for recognition of rarely used codons and restrict or expand codon recognition depending on their chemistries. A shift of the translational reading frame occurs in the absence of… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 80 extracted citations

Noncanonical Amino Acids

Methods in Molecular Biology • 2018
View 7 Excerpts
Highly Influenced

Elongator, a conserved multitasking complex?

Molecular microbiology • 2010
View 3 Excerpts
Highly Influenced

References

Publications referenced by this paper.
Showing 1-10 of 56 references

Effects of a minor isoleucyl tRNA on heterologous protein translation in Escherichia coli

TB JrDel, JM Ward, +6 authors JF Kane
J Bacteriol • 1995
View 3 Excerpts
Highly Influenced

Similar Papers

Loading similar papers…