t(9;13)(q34;q12) chromosomal translocation persisting 4 years post autologous bone marrow transplantation for secondary AML despite morphological remission.

@article{Mahendra1996t913q34q12CT,
  title={t(9;13)(q34;q12) chromosomal translocation persisting 4 years post autologous bone marrow transplantation for secondary AML despite morphological remission.},
  author={Premini Mahendra and E Michael Richards and Peter J Sinclair and Elisabeth P. Nacheva and R E Marcus},
  journal={Clinical and laboratory haematology},
  year={1996},
  volume={18 2},
  pages={121-2}
}
A 42-year-old male patient with a history of occupational exposure to benzene presented with pancytopenia. His bone marrow showed evidence of trilineage dysplasia and cytogenetic analysis revealed a unique t(9;13)(q34;q12) translocation. Five months after diagnosis he developed secondary AML. He was treated with four courses of chemotherapy and an autologous bone marrow transplantation (BMT). Four years post-transplantation he remains in haematological and morphological remission though the… CONTINUE READING