t(14;18) translocations in lymphocytes of healthy dioxin-exposed individuals from Seveso, Italy.

@article{Baccarelli2006t1418TI,
  title={t(14;18) translocations in lymphocytes of healthy dioxin-exposed individuals from Seveso, Italy.},
  author={Andrea A. Baccarelli and C. Hirt and Angela Cecilia Pesatori and Dario Consonni and Donald J. Patterson and Pier Alberto Bertazzi and Gottfried Doelken and Maria Teresa Landi},
  journal={Carcinogenesis},
  year={2006},
  volume={27 10},
  pages={2001-7}
}
Dioxin exposure has been associated with non-Hodgkin's lymphoma (NHL) in epidemiological investigations. The NHL-related t(14;18) translocations can be detected at a low copy number in lymphocytes from healthy subjects. Exposure to NHL-associated carcinogens, such as dioxin or pesticides, may cause expansion of t(14;18)-positive clones. We investigated prevalence and frequency of circulating t(14;18)-positive lymphocytes in 144 healthy subjects from a population exposed to dioxin [plasma TCDD… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 14 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 43 references

CYP 1 A 1 and CYP 1 B 1 genotypes , haplotypes , and TCDD - induced gene expression in subjects from Seveso , Italy

  • M. T. Landi, L. L. Needham, G. Lucier, P. Mocarelli, P. A. Bertazzi, N. Caporaso
  • Toxicology
  • 2005

Similar Papers

Loading similar papers…