summaries summary of the supplement on single - cell analysis

  • Published 2011


Since the beginning of research on cell biology, say Stephen Quake and Tomer Kalisky in a Commentary, technological advances have driven biological understanding of the single cell. Early microscopes that permitted biologists to observe single cells have led, via molecular marking techniques and flow cytometry, to the ability to rapidly monitor dozens of markers on thousands of individual cells. But the scale of singlecell analysis has not stopped there. The authors discuss methodologies, such as microfluidics, that are enabling highly parallel genome-scale analysis at single-cell resolution. They consider new applications—including haplotyping of human cells and the analysis of complex bacterial populations—for whole-genome sequencing of single cells. (Nat. Methods 8, 311–314, 2011)

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@inproceedings{2011summariesSO, title={summaries summary of the supplement on single - cell analysis}, author={}, year={2011} }