suPAR: The Molecular Crystal Ball

@inproceedings{Thun2009suPARTM,
  title={suPAR: The Molecular Crystal Ball},
  author={Maria Thun\o and Betina Macho and Jesper Eugen-Olsen},
  booktitle={Disease markers},
  year={2009}
}
soluble urokinase Plasminogen Activator Receptor (suPAR) levels reflect inflammation and elevated suPAR levels are found in several infectious diseases and cancer. suPAR exists in three forms; suPAR(I-III), suPAR(II-III) and suPAR(I) which show different properties due to structural differences. Studies suggest that full-length suPAR is a regulator of uPAR/uPA by actingas uPA-scavenger, whereas the cleaved suPAR(II-III) act as a chemotactic agent promoting the immune response via the SRSRY… CONTINUE READING
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