spo0J is required for normal chromosome segregation as well as the initiation of sporulation in Bacillus subtilis.

@article{Ireton1994spo0JIR,
  title={spo0J is required for normal chromosome segregation as well as the initiation of sporulation in Bacillus subtilis.},
  author={K Ireton and Nereus W. Gunther and Alan D Grossman},
  journal={Journal of bacteriology},
  year={1994},
  volume={176 17},
  pages={5320-9}
}
The spo0J gene of Bacillus subtilis is required for the initiation of sporulation. We show that the sporulation defect caused by null mutations in spo0J is suppressed by a null mutation in the gene located directly upstream from spo0J, soj (suppressor of spo0J). These results indicate that Soj inhibits the initiation of sporulation and that Spo0J antagonizes that inhibition. Further genetic experiments indicated that Soj ultimately affects sporulation by inhibiting the activation… CONTINUE READING
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