sigma(B) activity in Staphylococcus aureus is controlled by RsbU and an additional factor(s) during bacterial growth.

@article{Palma2001sigmaBAI,
  title={sigma(B) activity in Staphylococcus aureus is controlled by RsbU and an additional factor(s) during bacterial growth.},
  author={M Palma and Ambrose L. Cheung},
  journal={Infection and immunity},
  year={2001},
  volume={69 12},
  pages={7858-65}
}
Two genes of the sigB operon, rsbU and rsbV, were deleted in an rsbU(+) strain (FDA486) to evaluate the contribution of these two genes to sigma(B) activity in Staphylococcus aureus. The sigma(B) protein level and the transcription of two sigma(B)-dependent promoters (sigB and sarA P3 transcripts) were analyzed in the constructed mutants. A deletion of the first gene (rsbU) within the sigB operon led only to a partial reduction in sigma(beta) activity. A deletion of the second gene (rsbV… CONTINUE READING