siRNA delivery systems for cancer treatment.

@article{Oh2009siRNADS,
  title={siRNA delivery systems for cancer treatment.},
  author={Y B Oh and Tae Gwan Park},
  journal={Advanced drug delivery reviews},
  year={2009},
  volume={61 10},
  pages={850-62}
}
With increasing knowledge on the molecular mechanisms of endogenous RNA interference, small interfering RNAs (siRNAs) have been emerging as innovative nucleic acid medicines for treatment of incurable diseases such as cancers. Although several siRNA candidates for the treatment of ocular and respiratory diseases are undergoing clinical trials, there are challenges inherent in the further development of siRNAs for anti-cancer therapeutics, because systemic administration will be required in most… CONTINUE READING
191 Citations
147 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 191 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 147 references

A

  • T. I. Novobrantseva, A. Akinc, A. Borodovsky
  • de Fougerolles, Delivering silence: advancements…
  • 2008

Similar Papers

Loading similar papers…