secD, a new gene involved in protein export in Escherichia coli.

  title={secD, a new gene involved in protein export in Escherichia coli.},
  author={Claudette Gardel and Steve Benson and John Francis Hunt and Susan Michaelis and Jon et Beckwith},
  journal={Journal of bacteriology},
  volume={169 3},
New mutants of Escherichia coli altered in protein export were identified in phoA-lacZ and lamB-lacZ gene fusion strains by searching for mutants that showed an altered lactose phenotype. Several mutations mapped in a new gene, secD. These mutants were, in general, cold sensitive for growth, and the mutations led to an accumulation of precursor of exported proteins. The secD gene is closely linked to tsx on the E. coli chromosome, but separable from another gene proposed to be involved in… CONTINUE READING

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