sRNA Antitoxins: More than One Way to Repress a Toxin

@inproceedings{Wen2014sRNAAM,
  title={sRNA Antitoxins: More than One Way to Repress a Toxin},
  author={Jia Wen and Elizabeth M Fozo},
  booktitle={Toxins},
  year={2014}
}
Bacterial toxin-antitoxin loci consist of two genes: one encodes a potentially toxic protein, and the second, an antitoxin to repress its function or expression. The antitoxin can either be an RNA or a protein. For type I and type III loci, the antitoxins are RNAs; however, they have very different modes of action. Type I antitoxins repress toxin protein expression through interacting with the toxin mRNA, thereby targeting the mRNA for degradation or preventing its translation or both; type III… CONTINUE READING
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