rpoB Gene mutations and molecular characterization of rifampin-resistant Mycobacterium tuberculosis isolates from Shandong Province, China.

@article{Ma2006rpoBGM,
  title={rpoB Gene mutations and molecular characterization of rifampin-resistant Mycobacterium tuberculosis isolates from Shandong Province, China.},
  author={Xin Ma and Haiying Wang and Yunfeng Deng and Zhi-min Liu and Yong Xu and Xi Qing Pan and James M Musser and Edward A. Graviss},
  journal={Journal of clinical microbiology},
  year={2006},
  volume={44 9},
  pages={
          3409-12
        }
}
  • Xin Ma, Haiying Wang, +5 authors Edward A. Graviss
  • Published 2006
  • Medicine, Biology
  • Journal of clinical microbiology
  • Sixty rifampin (RIF)-resistant and 75 RIF-susceptible Mycobacterium tuberculosis isolates from Shandong Province, China, were analyzed for rpoB gene mutations and genotyped. Mycobacterial interspersed repetitive unit (MIRU) genotype 223325173533 was overrepresented among RIF-resistant isolates. MIRU combined with IS6110 restriction fragment length polymorphism analysis as the second-line genotyping method may reflect epidemiologic links more reliably than each method alone. 

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