roX RNAs are required for increased expression of X-linked genes in Drosophila melanogaster males.

@article{Deng2006roXRA,
  title={roX RNAs are required for increased expression of X-linked genes in Drosophila melanogaster males.},
  author={Xinxian Deng and Victoria H. Meller},
  journal={Genetics},
  year={2006},
  volume={174 4},
  pages={
          1859-66
        }
}
The male-specific lethal (MSL) ribonucleoprotein complex is necessary for equalization of X:A expression levels in Drosophila males, which have a single X chromosome. It binds selectively to the male X chromosome and directs acetylation of histone H4 at lysine 16 (H4Ac16), a modification linked to elevated transcription. roX1 and roX2 noncoding RNAs are essential but redundant components of this complex. Simultaneous removal of both roX RNAs reduces X localization of the MSL proteins and… CONTINUE READING

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Drosophila malespecific lethal2 protein : structure / function analysis and dependence on MSL1 for chromosome association

  • B. P. R attner
  • Genetics
  • 1997

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