recF and recR are required for the resumption of replication at DNA replication forks in Escherichia coli.

@article{Courcelle1997recFAR,
  title={recF and recR are required for the resumption of replication at DNA replication forks in Escherichia coli.},
  author={Justin Courcelle and Cathy Carswell-Crumpton and Philip C. Hanawalt},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={1997},
  volume={94 8},
  pages={3714-9}
}
Escherichia coli containing a mutation in recF are hypersensitive to UV. However, they exhibit normal levels of conjugational or transductional recombination unless the major pathway (recBC) is defective. This implies that the UV sensitivity of recF mutants is not due to a defect in recombination such as occurs during conjugation or transduction. Here, we show that when replication is disrupted, at least two genes in the recF pathway, recF and recR, are required for the resumption of… CONTINUE READING
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