ras gene mutations and HPV infection are common in human laryngeal carcinoma.

@article{Anwar1993rasGM,
  title={ras gene mutations and HPV infection are common in human laryngeal carcinoma.},
  author={Khursheed Anwar and Koichi Nakakuki and Hironobu Naiki and Manabu Inuzuka},
  journal={International journal of cancer},
  year={1993},
  volume={53 1},
  pages={
          22-8
        }
}
To evaluate the role of ras activation and human papillomavirus (HPV) infection in laryngeal carcinoma, we analyzed tumor DNA from 43 cases, including 25 primary laryngeal tumors, 12 lymph-node and one skin metastases, and 5 recurrent laryngeal carcinomas. Thirteen normal laryngeal tissues and 7 benign laryngeal nodule biopsy specimens along with normal tissue surrounding laryngeal carcinoma in 2 cases were also included. The polymerase-chain-reaction technique was used to amplify DNA fragments… CONTINUE READING
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Human papillomavirus infection and epidermal growth factor receptor expression in primary laryngeal squamous cell carcinoma.

Clinical cancer research : an official journal of the American Association for Cancer Research • 2001