rSW-seq: Algorithm for detection of copy number alterations in deep sequencing data

@inproceedings{Kim2009rSWseqAF,
  title={rSW-seq: Algorithm for detection of copy number alterations in deep sequencing data},
  author={Tae-Min Kim and Lovelace J. Luquette and Ruibin Xi and Peter J. Park},
  booktitle={BMC Bioinformatics},
  year={2009}
}
Recent advances in sequencing technologies have enabled generation of large-scale genome sequencing data. These data can be used to characterize a variety of genomic features, including the DNA copy number profile of a cancer genome. A robust and reliable method for screening chromosomal alterations would allow a detailed characterization of the cancer genome with unprecedented accuracy. We develop a method for identification of copy number alterations in a tumor genome compared to its matched… CONTINUE READING
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