q-space and conventional diffusion imaging of axon and myelin damage in the rat spinal cord after axotomy.

@article{Farrell2010qspaceAC,
  title={q-space and conventional diffusion imaging of axon and myelin damage in the rat spinal cord after axotomy.},
  author={Jonathan A. D. Farrell and Jiangyang Zhang and Melina V. Jones and Cynthia A Deboy and Paul Ned Hoffman and Bennett A. Landman and Seth A. Smith and Daniel S. Reich and Peter A. Calabresi and P C M van Zijl},
  journal={Magnetic resonance in medicine},
  year={2010},
  volume={63 5},
  pages={1323-35}
}
Parallel and perpendicular diffusion properties of water in the rat spinal cord were investigated 3 and 30 days after dorsal root axotomy, a specific insult resulting in early axonal degeneration followed by later myelin damage in the dorsal column white matter. Results from q-space analysis (i.e., the diffusion probability density function) obtained with strong diffusion weighting were compared to conventional anisotropy and diffusivity measurements at low b-values, as well as to histology for… CONTINUE READING

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