q‐Space imaging of the brain

@article{King1994qSpaceIO,
  title={q‐Space imaging of the brain},
  author={M. D. King and J. Houseman and S. Roussel and N. van Bruggen and S. Williams and D. Gadian},
  journal={Magnetic Resonance in Medicine},
  year={1994},
  volume={32}
}
q‐Space imaging (Callaghan, J. Magn. Reson. 88,493 (1990)) has been used to obtain mouse brain water displacement profiles. These profiles take the form of a unidirectional incoherent‐displacement probability density distribution. Two groups of mice were studied, a normal group and one in which surgery had been performed to reduce the supply of blood to the forebrain. In the normal group the incoherent displacement of water was reducedpostmortem. Four of the surgically treated mice yielded… Expand
Localized q‐space imaging of the mouse brain
TLDR
Localized q‐space imaging was used to obtain water displacement profiles from mouse brain that take the form of unidirectional diffusive displacement probability distributions, consistent with the diffusion‐weighted image intensity changes that occur after a period of ischemia. Expand
In vivo visualization of displacement-distribution-derived parameters in q-space imaging.
TLDR
The results indicate that in vivo q-space analysis is a potential tool for the assessment of different cerebral water components, and it might extend the diagnostic interpretation of data from diffusion magnetic resonance imaging. Expand
Displacement imaging of spinal cord using q‐space diffusion‐weighted MRI
TLDR
It was found that changes in the diffusion characteristics of white matter upon maturation are responsible for the emergence of gray/white matter contrast and this new imaging methodology was used to follow spinal cord maturation in the rat. Expand
Assignment of the water slow‐diffusing component in the central nervous system using q‐space diffusion MRS: Implications for fiber tract imaging
TLDR
In vitro and in situ diffusion‐weighted images with high b values were acquired to obtain highly detailed images of white matter Fiber tracts in the central nervous system, which provide detailed information on white matter fiber tract location and allow spinal cord maturation to be followed with high accuracy. Expand
Effect of experimental parameters on high b‐value q‐space MR images of excised rat spinal cord
TLDR
It was found that long δ and long TE overemphasizes the apparent slow‐diffusing water component of the SC, which is also the more restricted one, and it is demonstrated that the single‐component q‐space analysis best describes diffusion in WM when diffusion is measured perpendicular to the fibers of theSC. Expand
Application of q-Space Diffusion MRI for the Visualization of White Matter
TLDR
The results suggest that the myelin map, a kurtosis-related heat map obtainable with time-saving QSI, may be a novel and clinically useful means of visualizing myelin in the human CNS. Expand
q-Space imaging using small magnetic field gradient.
TLDR
This work proposes a method to obtain certain quantities that indicate a characteristic of the diffusion and that uses low q-value measurements, and tries to map the moments and kurtosis using clinical MR imaging equipment. Expand
Biexponential diffusion attenuation in various states of brain tissue: Implications for diffusion‐weighted imaging
TLDR
It is demonstrated that the changes in f1 and f2 occur simultaneously to those in the extracellular and intracellular space fractions during: (i) cell swelling after total circulatory arrest, and (ii) the recovery from N‐methyl‐D‐aspartate induced excitotoxic brain edema evoked by MK‐801, as measured by changes in the electrical impedance. Expand
Structural information in neuronal tissue as revealed by q‐space diffusion NMR spectroscopy of metabolites in bovine optic nerve
TLDR
It is concluded that q‐space analysis of metabolite diffusion enables extraction of structural information about the sample, and that the diffusion of the metabolites in optic nerve is dictated mainly by the cellular medium and microstructure of the tissue. Expand
Isotropic q-space Analytical map using 3D Diffusion MR Imaging
A q-space diffusion MR imaging is able to detect microstructure (10μm ∼ ) dynamically. Recently this method is suggested as investigating neuronal generation and degeneration in spinal cord. TheExpand
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