pharmacotherapy Update : pregabalin in the Treatment of Generalized Anxiety Disorder

  title={pharmacotherapy Update : pregabalin in the Treatment of Generalized Anxiety Disorder},
  author={Stuart A. Montgomery and Siegfried Kasper},
Generalized anxiety disorder (GAD) is a common disorder that is chronic, disabling, and often goes undiagnosed. Currently, four distinct classes of medications have demonstrated efficacy in the treatment of GAD: benzodiazepines, serotonin and/or norepinephrine reuptake inhibitors (SSRIs/SNRIs), histamine H1 receptor blockers (hydroxyzine), and pregabalin. Pregabalin acts via binding to an α2-δ subunit presynaptic membrane protein that inhibits neurotransmitter release in excited neurons… CONTINUE READING


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AV Joshi, FS Mandel, E Schweizer, BK Herman
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Efficacy and tolerability of pregabalin in patients with generalized anxiety disorder in everyday clinical practice

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