pfmdr2 confers heavy metal resistance to Plasmodium falciparum.

@article{Rosenberg2006pfmdr2CH,
  title={pfmdr2 confers heavy metal resistance to Plasmodium falciparum.},
  author={Elli Rosenberg and Ilena Litus and Nurit Schwarzfuchs and Rosa Sinay and Pnina Schlesinger and Jacob Golenser and Stefan Baumeister and Klaus R. Lingelbach and Yaakov Pollack},
  journal={The Journal of biological chemistry},
  year={2006},
  volume={281 37},
  pages={27039-45}
}
Heavy metals are required by all organisms for normal function, but high levels of heavy metals are toxic. Therefore, homeostasis of these metals is crucial. In the human malaria-causing agent Plasmodium falciparum, the mechanisms of heavy metal transport have yet to be characterized. We have developed a P. falciparum line resistant to heavy metals from a wild-type line sensitive to heavy metals. A molecular and biochemical analysis of the involvement of the P. falciparum multidrug resistance 2… CONTINUE READING
15 Citations
0 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 15 extracted citations

Similar Papers

Loading similar papers…