peroxireduxin-4 is Over-expressed in colon cancer and its Down-Regulation Leads to Apoptosis

@inproceedings{Leydold2011peroxireduxin4IO,
  title={peroxireduxin-4 is Over-expressed in colon cancer and its Down-Regulation Leads to Apoptosis},
  author={Sandra M. Leydold and Michael Seewald and Christian Stratowa and Klaus Kaserer and Wolfgang Sommergruber and Norbert Kraut and Norbert Schweifer},
  year={2011}
}
The objective of this study was to gain insight into the biological basis of colon cancer progression by characterizing gene expression differences between normal colon epithelium, corresponding colorectal primary tumors and metastases. We found a close similarity in gene expression patterns between primary tumors and metastases, indicating a correlation between gene expression and morphological characteristics. PRDX4 was identified as highly expressed both in primary colon tumors and… CONTINUE READING