parSRA: A framework for the parallel execution of short read aligners on compute clusters

Abstract

The growth of next generation sequencing datasets poses as a challenge to the alignment of reads to reference genomes in terms of both accuracy and speed. In this work we present parSRA, a parallel framework to accelerate the execution of existing short read aligners on distributed-memory systems. parSRA can be used to parallelize a variety of short read… (More)
DOI: 10.1016/j.jocs.2017.01.008

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