pSTAT1, pSTAT3, and T-bet expression in peripheral blood mononuclear cells from relapsing-remitting multiple sclerosis patients correlates with disease activity.

@article{Frisullo2006pSTAT1PA,
  title={pSTAT1, pSTAT3, and T-bet expression in peripheral blood mononuclear cells from relapsing-remitting multiple sclerosis patients correlates with disease activity.},
  author={Giovanni Frisullo and Francesco Angelucci and Marcella Caggiula and Viviana Nociti and Raffaele Iorio and Agata Katia Patanella and Cristina Sancricca and Massimiliano Mirabella and Pietro A. Tonali and Anna Paola Batocchi},
  journal={Journal of neuroscience research},
  year={2006},
  volume={84 5},
  pages={1027-36}
}
Multiple sclerosis (MS) is a chronic inflammatory demyelinating disease of the central nervous system, and it is considered to be a T helper 1 (Th1) cell-mediated autoimmune disease. T-bet has been identified as a key transcription factor for the development of Th1 cells and the induction of interferon (IFN)-gamma production. T-bet is induced during T-cell activation by the IFN-gamma signal transducer and activator of transcription (STAT)-1 signalling pathway. In this study we found an up… CONTINUE READING
53 Citations
0 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 53 extracted citations

Similar Papers

Loading similar papers…