pO polarography, contrast enhanced color duplex sonography (CDS), [18F] fluoromisonidazole and [18F] fluorodeoxyglucose positron emission tomography: validated methods for the evaluation of therapy-relevant tumor oxygenation or only bricks in the puzzle of tumor hypoxia?

@article{Gagel2006pOPC,
  title={pO polarography, contrast enhanced color duplex sonography (CDS), [18F] fluoromisonidazole and [18F] fluorodeoxyglucose positron emission tomography: validated methods for the evaluation of therapy-relevant tumor oxygenation or only bricks in the puzzle of tumor hypoxia?},
  author={Bernd Gagel and Marc Dieter Piroth and Michael Pinkawa and Patrick Reinartz and Michael Zimny and Hans Juergen Kaiser and Sven Stanzel and Branka Asadpour and Cengiz Demirel and Kurt Hamacher and Heinz Hubert Coenen and Thomas Manfred Scholbach and Payam Maneschi and Ercole Dimartino and Michael J. Eble},
  journal={BMC Cancer},
  year={2006},
  volume={7},
  pages={113 - 113}
}
The present study was conducted to analyze the value of ([18F] fluoromisonidazole (FMISO) and [18F]-2-fluoro-2'-deoxyglucose (FDG) PET as well as color pixel density (CPD) and tumor perfusion (TP) assessed by color duplex sonography (CDS) for determination of therapeutic relevant hypoxia. As a standard for measuring tissue oxygenation in human tumors, the invasive, computerized polarographic needle electrode system (pO2 histography) was used for comparing the different non invasive measurements… CONTINUE READING

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Effect of intratumoral heterogeinity in oxygenation status on FMISO PET, autoradiography, and electrode pO2 measurements in murine tumors

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