pH sensitive interpenetrating network microgels of sodium alginate‐acrylic acid for the controlled release of ibuprofen

@inproceedings{Babu2006pHSI,
  title={pH sensitive interpenetrating network microgels of sodium alginate‐acrylic acid for the controlled release of ibuprofen},
  author={Vemuluri Ramesh Babu and K S V Krishna Rao and Malladi Sairam and Boya Vijaya Kumar Naidu and Kallappa M. Hosamani and Tejraj M. Aminabhavi},
  year={2006}
}
pH-Sensitive interpenetrating network (IPN) microgels (MGs) of sodium alginate (NaAlg) and acrylic acid have been prepared by using water-in-oil (W/O) emulsion technique. The MGs were characterized by Fourier transform infrared spectroscopy (FTIR), differential scanning calorimetry (DSC), X-ray diffractometer (X-RD). The release of ibuprofen (IB), an anti-inflammatory drug, from these MGs was studied in pH 1.2 and 7.4 media. MG network consists of NaAlg, which disintegrates in the intestinal… CONTINUE READING

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