pH-dependent effect of mitochondria on calcium influx into Jurkat cells; a novel mechanism of cell protection against calcium entry during energy stress.

Abstract

Loss of the mitochondrial membrane potential results in a significant inhibition of calcium influx through calcium release-activated channels (CRAC) in Jurkat cells suspended in the medium of pH lower than 7.4. This effect disappears when the medium pH increases. Alkalinisation of the cytosol achieved by the addition of NH(4)Cl to the cells pretreated with… (More)

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Cite this paper

@article{Zablocki2003pHdependentEO, title={pH-dependent effect of mitochondria on calcium influx into Jurkat cells; a novel mechanism of cell protection against calcium entry during energy stress.}, author={Krzysztof Zablocki and Agnieszka Makowska and Jerzy Duszyński}, journal={Cell calcium}, year={2003}, volume={33 2}, pages={91-9} }