pH-dependent Ca2+ binding to the F0 c-subunit affects proton translocation of the ATP synthase from Synechocystis 6803.

@article{Walraven2002pHdependentCB,
  title={pH-dependent Ca2+ binding to the F0 c-subunit affects proton translocation of the ATP synthase from Synechocystis 6803.},
  author={Hendrika S Van Walraven and Marijke J. C. Scholts and Stanislav D. Zakharov and Ruud Kraayenhof and Richard A. Dilley},
  journal={Journal of bioenergetics and biomembranes},
  year={2002},
  volume={34 6},
  pages={455-64}
}
It was shown before (Wooten, D. C., and Dilley, R. A. (1993) J. Bioenerg. Biomembr. 25, 557-567; Zakharov, S. D., Li, X., Red'ko, T. P., and Dilley, R. A. (1996) J. Bioenerg. Biomembr. 28, 483-493) that pH dependent reversible Ca2+ binding near the N- and C-terminal end of the 8 kDa subunit c modulates ATP synthesis driven by an applied pH jump in chloroplast and E. coli ATP synthase due to closing a "proton gate" proposed to exist in the F0 H+ channel of the F0F1 ATP synthase. This mechanism… CONTINUE READING