pH dependence of influenza A virus-induced haemolysis is determined by the haemagglutinin gene.

@article{Lenard1982pHDO,
  title={pH dependence of influenza A virus-induced haemolysis is determined by the haemagglutinin gene.},
  author={John Lenard and Carole Bailey and Douglas K. Miller},
  journal={The Journal of general virology},
  year={1982},
  volume={62 (Pt 2)},
  pages={353-5}
}
The pH-dependent profiles of haemolysis by influenza viruses AHK/8/68 (HK virus) and APR/8/34 (PR8 virus) were found to possess characteristic differences. Both viruses were highly haemolytic at pH 5.0, but while HK virus-induced haemolysis was undetectable above pH 5.5 to 5.6,, PR8 virus-induced haemolysis persisted at higher pH values, becoming undetectable above pH 5.7 to 5.8. In order to determine whether these haemolysis profiles were genetically determined, we studied the pH dependence of… CONTINUE READING