pH and reduction dual-bioresponsive polymersomes for efficient intracellular protein delivery.

@article{Zhang2012pHAR,
  title={pH and reduction dual-bioresponsive polymersomes for efficient intracellular protein delivery.},
  author={Jinchao Zhang and Liangliang Wu and Fenghua Meng and Zhongjuan Wang and Chao Deng and Haiyan Liu and Zhiyuan Zhong},
  journal={Langmuir : the ACS journal of surfaces and colloids},
  year={2012},
  volume={28 4},
  pages={2056-65}
}
pH and reduction dual-bioresponsive nanosized polymersomes based on poly(ethylene glycol)-SS-poly(2-(diethyl amino)ethyl methacrylate) (PEG-SS-PDEA) diblock copolymers were developed for efficient encapsulation and triggered intracellular release of proteins. PEG-SS-PDEA copolymers with PDEA-block molecular weights ranging from 4.7, 6.8, to 9.2 kg/mol were… CONTINUE READING