pANCA Antibodies in Patients with Anterior Uveitis: Identification of a Marker Antibody Usually Associated with Ulcerative Colitis

@article{Gordon1998pANCAAI,
  title={pANCA Antibodies in Patients with Anterior Uveitis: Identification of a Marker Antibody Usually Associated with Ulcerative Colitis},
  author={Lynn Gordon and Mark P. Eggena and Gary Holland and James M. Weisz and Jonathan Braun},
  journal={Journal of Clinical Immunology},
  year={1998},
  volume={18},
  pages={264-271}
}
A pANCA autoantibody (antineutrophil cytoplasmic antibody, perinuclear pattern) has been described in uveitis patients, but its correlation with systemic illnesses and the specific type of pANCA has not been defined. The goals of this study were to determine the (1) frequency of pANCA autoantibodies in uveitis, (2) systemic associations in the pANCA+ uveitis patients, and (3) type of pANCA antigen recognized by the uveitis-associated autoantibody. Serum was obtained from 59 patients with… CONTINUE READING
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