p73 G4C14-to-A4T14 gene polymorphism and interaction with p53 exon 4 Arg72Pro on cancer susceptibility: a meta-analysis of the literature.

@article{Feo2012p73GG,
  title={p73 G4C14-to-A4T14 gene polymorphism and interaction with p53 exon 4 Arg72Pro on cancer susceptibility: a meta-analysis of the literature.},
  author={Emma De Feo and Benedetto Simone and Rachel Simo Kamgaing and Paola Gall{\`i} and Nobuyuki Hamajima and Zhibin Hu and Guojun Li and Yan Li and Keitaro Matsuo and Jae Yong Park and Susanta Roychoudhury and Margaret R. Spitz and Qingyi Wei and Jianhui Zhang and Walter Ricciardi and Stefania Boccia},
  journal={Mutagenesis},
  year={2012},
  volume={27 3},
  pages={267-73}
}
The p73 gene (1p36-33) is involved in cancer development through cell growth inhibition by inducing apoptosis in a p53-like manner. The p73 G4C14-to-A4T14 dinucleotide polymorphism, consisting of two single-nucleotide polymorphisms in the non-coding region of exon 2 that are in complete linkage disequilibrium, has been extensively studied in association with cancer risk. We performed a meta-analysis of published studies that examined the association between this p73 G4C14-to-A4T14 polymorphism… CONTINUE READING
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